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Robust nuclear lamina-based cell classification of aging and senescent cells

Changes in the shape of the nuclear lamina are exhibited in senescent cells, as well as in cells expressing mutations in lamina genes. To identify cells with defects in the nuclear lamina we developed an imaging method that quantifies the intensity and curvature of the nuclear lamina. We show that t...

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Detalhes bibliográficos
Main Authors: Righolt, Christiaan H., van 't Hoff, Merel L.R., Vermolen, Bart J., Young, Ian T., Raz, Vered
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273899/
https://ncbi.nlm.nih.gov/pubmed/22199022
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