An Overview of the CNS-Pharmacodynamic Profiles of Nonselective and Selective GABA Agonists

Various α (2,3) subtype selective partial GABA-A agonists are in development to treat anxiety disorders. These compounds are expected to be anxiolytic with fewer undesirable side effects, compared to nonselective GABA-A agonists like benzodiazepines. Several α (2,3) subtype selective and nonselectiv...

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Bibliographic Details
Main Authors: Chen, Xia, de Haas, Sanne, de Kam, Marieke, van Gerven, Joop
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273701/
https://ncbi.nlm.nih.gov/pubmed/22363345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/134523
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