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T-bet employs diverse regulatory mechanisms to repress transcription

Lineage-defining transcription factors are responsible for activating the signature genes required for a given cell fate. They are also needed to repress the genetic programs associated with alternative lineage decisions. The T-box transcription factor T-bet is required for CD4(+) T helper 1 cell di...

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Detalhes bibliográficos
Main Authors: Oestreich, Kenneth J., Weinmann, Amy S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273642/
https://ncbi.nlm.nih.gov/pubmed/22133865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2011.10.005
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