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The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns
The T-box transcription factor T-bet is important for the differentiation of naive CD4(+) T helper cells (Th cells) into the Th1 phenotype. Much is known about T-bet’s role as a transcriptional activator, but less is known about the mechanisms by which T-bet functionally represses alternative Th cel...
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| 主要な著者: | , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092354/ https://ncbi.nlm.nih.gov/pubmed/21518797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102144 |
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