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Diverse functions of distal regulatory elements at the IFNG locus

Previous studies have identified multiple conserved noncoding sequences (CNS) at the mouse Ifng locus sufficient for enhancer activity in cell-based assays. These studies do not directly address biology of the human IFNG locus in a genomic setting. IFNG enhancers may be functionally redundant or eac...

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Autors principals: Collins, Patrick L., Henderson, Melodie A., Aune, Thomas M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273639/
https://ncbi.nlm.nih.gov/pubmed/22246629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102879
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