Llwytho...
Domain coupling in GPCRs: the engine for induced conformational changes
Recent solved structures of G protein-coupled receptors (GPCRs) provide insights into variation of the structure and molecular mechanisms of GPCR activation. In this review we provide evidence for the emerging paradigm of domain coupling facilitated by intrinsic disorder of the ligand-free state in...
Wedi'i Gadw mewn:
| Prif Awduron: | , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2011
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3273637/ https://ncbi.nlm.nih.gov/pubmed/22037017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2011.09.007 |
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