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Trisomy and early brain development

Trisomy for human chromosome 21 (Hsa21) results in Down syndrome (DS). The finished human genome sequence provides a thorough catalog of the genetic elements whose altered dosage perturbs development and function in DS. However, understanding how small alterations in the steady state transcript leve...

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Sonraí Bibleagrafaíochta
Main Authors: Haydar, Tarik F., Reeves, Roger H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273608/
https://ncbi.nlm.nih.gov/pubmed/22169531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2011.11.001
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