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Trisomy 21 and Facial Developmental Instability
The most common live-born human aneuploidy is trisomy 21, which causes Down syndrome (DS). Dosage imbalance of genes on chromosome 21 (Hsa21) affects complex gene-regulatory interactions and alters development to produce a wide range of phenotypes, including characteristic facial dysmorphology. Litt...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3744194/ https://ncbi.nlm.nih.gov/pubmed/23505010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajpa.22255 |
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