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ExoS and ExoT ADP-ribosyltransferase activities mediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival()

P. aeruginosa is a leading cause of blinding corneal ulcers worldwide. To determine the role of type III secretion in the pathogenesis of P. aeruginosa keratitis, corneas of C57BL/6 mice were infected with P. aeruginosa strain PAO1 or PAK, which express ExoS, ExoT and ExoY, but not ExoU. PAO1 and PA...

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Detalhes bibliográficos
Main Authors: Sun, Yan, Karmakar, Mausita, Taylor, Patricia R., Rietsch, Arne, Pearlman, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273577/
https://ncbi.nlm.nih.gov/pubmed/22250085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102148
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