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The DNA damage response in viral-induced cellular transformation

The DNA damage response (DDR) has emerged as a critical tumour suppressor pathway responding to cellular DNA replicative stress downstream of aberrant oncogene over-expression. Recent studies have now implicated the DDR as a sensor of oncogenic virus infection. In this review, we discuss the mechani...

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Detalhes bibliográficos
Main Authors: Nikitin, P A, Luftig, M A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273341/
https://ncbi.nlm.nih.gov/pubmed/22240795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.612
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