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Preclinical validation of a multiplex real-time assay to quantify SMN mRNA in patients with SMA
OBJECTIVE: To determine whether survival motor neuron (SMN) expression was stable over time. METHODS: We developed a multiplex real-time reverse transcriptase (RT)-PCR assay to quantify SMN transcripts in preclinical blood samples from 42 patients with spinal muscular atrophy (SMA) drawn for three t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3273325/ https://ncbi.nlm.nih.gov/pubmed/17283322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/01.wnl.0000252934.70676.ab |
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