The reactions of thiouridines and thiouracils with chloroacetaldehyde; mechanistic considerations.

2-Thiouridine, 4-thiouridine and the corresponding thiouracils were quantitatively modified with aqueous chloroacetaldehyde /37 degrees C, pH 3.0--6.5/. The rate-pH dependence found for the disappearance of the substrates suggested initial S-alkylation. The unstable S-acetaldehydyl intermediates wer...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Krzyzosiak, W J, Biernat, J, Ciesiołka, J, Górnicki, P, Wiewiórowski, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1980
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327317/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7433118/
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