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Intersectin 1 Enhances Cbl Ubiquitylation of Epidermal Growth Factor Receptor through Regulation of Sprouty2-Cbl Interaction

Ubiquitylation of receptor tyrosine kinases plays a critical role in regulating the trafficking and lysosomal degradation of these important signaling molecules. We identified the multidomain scaffolding protein intersectin 1 (ITSN1) as an important regulator of this process (N. P. Martin et al., Mo...

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מידע ביבליוגרפי
Main Authors: Okur, Mustafa Nazir, Ooi, Jolene, Fong, Chee Wai, Martinez, Natalia, Garcia-Dominguez, Carlota, Rojas, Jose M., Guy, Graeme, O'Bryan, John P.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272971/
https://ncbi.nlm.nih.gov/pubmed/22158968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05647-11
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