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Vpr-Binding Protein Antagonizes p53-Mediated Transcription via Direct Interaction with H3 Tail

HIV-1 Vpr-binding protein (VprBP) has been implicated in the regulation of both DNA replication and cell cycle progression, but its precise role remains unclear. Here we report that VprBP regulates the p53-induced transcription and apoptotic pathway. VprBP is recruited to p53-responsive promoters an...

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Bibliografische gegevens
Hoofdauteurs: Kim, Kyunghwan, Heo, Kyu, Choi, Jongkyu, Jackson, Sarah, Kim, Hyunjung, Xiong, Yue, An, Woojin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272969/
https://ncbi.nlm.nih.gov/pubmed/22184063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06037-11
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