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Vpr-Binding Protein Antagonizes p53-Mediated Transcription via Direct Interaction with H3 Tail
HIV-1 Vpr-binding protein (VprBP) has been implicated in the regulation of both DNA replication and cell cycle progression, but its precise role remains unclear. Here we report that VprBP regulates the p53-induced transcription and apoptotic pathway. VprBP is recruited to p53-responsive promoters an...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272969/ https://ncbi.nlm.nih.gov/pubmed/22184063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06037-11 |
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