Effect of the cannabinoid receptor–1 antagonist rimonabant on inflammation in mice with diet-induced obesity

We studied whether CB1 blockade with rimonabant has an anti-inflammatory effect in obese mice, and whether this effect depends on weight loss and/or diet consumption. High-fat diet (HFD)–induced obese mice were treated orally with rimonabant (HFD-R) or vehicle (HFD-V) for 4 weeks. Paired-feeding was...

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Main Authors: Wang, Qun, Perrard, Xiaoyuan Dai, Perrard, Jerry L., Mansoori, Amir, Smith, C. Wayne, Ballantyne, Christie M., Wu, Huaizhu
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272877/
https://ncbi.nlm.nih.gov/pubmed/20885384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2010.213
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