An Angiotensin II Type 1 Receptor Blocker Prevents Renal Injury via Inhibition of the Notch Pathway in Ins2 Akita Diabetic Mice

Recently, it has been reported that the Notch pathway is involved in the pathogenesis of diabetic nephropathy. In this study, we investigated the activation of the Notch pathway in Ins2 Akita diabetic mouse (Akita mouse) and the effects of telmisartan, an angiotensin II type1 receptor blocker, on th...

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Main Authors: Koshizaka, Masaya, Takemoto, Minoru, Sato, Seiya, Tokuyama, Hirotake, Fujimoto, Masaki, Okabe, Emiko, Ishibashi, Ryoichi, Ishikawa, Takahiro, Tsurutani, Yuya, Onishi, Shunichiro, Mezawa, Morito, He, Peng, Honjo, Satoshi, Ueda, Shiro, Saito, Yasushi, Yokote, Koutaro
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272808/
https://ncbi.nlm.nih.gov/pubmed/22319521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/159874
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