An Angiotensin II Type 1 Receptor Blocker Prevents Renal Injury via Inhibition of the Notch Pathway in Ins2 Akita Diabetic Mice

Recently, it has been reported that the Notch pathway is involved in the pathogenesis of diabetic nephropathy. In this study, we investigated the activation of the Notch pathway in Ins2 Akita diabetic mouse (Akita mouse) and the effects of telmisartan, an angiotensin II type1 receptor blocker, on th...

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Autori principali: Koshizaka, Masaya, Takemoto, Minoru, Sato, Seiya, Tokuyama, Hirotake, Fujimoto, Masaki, Okabe, Emiko, Ishibashi, Ryoichi, Ishikawa, Takahiro, Tsurutani, Yuya, Onishi, Shunichiro, Mezawa, Morito, He, Peng, Honjo, Satoshi, Ueda, Shiro, Saito, Yasushi, Yokote, Koutaro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272808/
https://ncbi.nlm.nih.gov/pubmed/22319521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/159874
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