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Inhibition of cowpox virus and monkeypox virus infection by mitoxantrone

Mitoxantrone, an FDA-approved therapeutic for the treatment of cancer and multiple sclerosis, was previously reported to exhibit antiviral activity against vaccinia virus. To determine whether this activity extends to other orthopoxviruses, mitoxantrone was tested against cowpox and monkeypox. Mitox...

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Bibliografiske detaljer
Main Authors: Altmann, Sharon E., Smith, Alvin L., Dyall, Julie, Johnson, Reed F., Dodd, Lori E., Jahrling, Peter B., Paragas, Jason, Blaney, Joseph E.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272698/
https://ncbi.nlm.nih.gov/pubmed/22182595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2011.12.001
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