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Inhibition of cowpox virus and monkeypox virus infection by mitoxantrone

Mitoxantrone, an FDA-approved therapeutic for the treatment of cancer and multiple sclerosis, was previously reported to exhibit antiviral activity against vaccinia virus. To determine whether this activity extends to other orthopoxviruses, mitoxantrone was tested against cowpox and monkeypox. Mitox...

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Detalhes bibliográficos
Main Authors: Altmann, Sharon E., Smith, Alvin L., Dyall, Julie, Johnson, Reed F., Dodd, Lori E., Jahrling, Peter B., Paragas, Jason, Blaney, Joseph E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272698/
https://ncbi.nlm.nih.gov/pubmed/22182595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2011.12.001
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