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Altered IL-6 receptor, IL-6R and gp130, production and expression and decreased SOCS-3 expression in placentas from women with preeclampsia

IL-6 and its receptor complex, IL-6 receptor (IL-6R) and gp130, are critical in induction of suppressor of cytokine signaling-3 (SOCS-3) protein, a negative cytokine regulator and anti-inflammatory mediator, in a biological system. Increased inflammatory response is believed to contribute to the pla...

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Autors principals: Zhao, Shuang, Gu, Yang, Dong, Qin, Fan, Ruping, Wang, Yuping
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272491/
https://ncbi.nlm.nih.gov/pubmed/18986700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2008.09.011
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