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Cysteinyl leukotriene type I receptor desensitization sustains Ca(2+)-dependent gene expression

A universal mechanism to turn off a biological response is receptor desensitization, where the ability of a physiological trigger to activate a cell is lost despite the continued presence of the stimulus. Receptor desensitization of G protein-coupled receptors involves uncoupling of the receptor fro...

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Библиографические подробности
Главные авторы: Ng, Siaw-Wei, Bakowski, Daniel, Nelson, Charmaine, Mehta, Ravi, Almeyda, Robert, Bates, Grant, Parekh, Anant B.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272478/
https://ncbi.nlm.nih.gov/pubmed/22230957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10731
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