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Coupling of Ca(2+) Microdomains to Spatially and Temporally Distinct Cellular Responses by the Tyrosine Kinase Syk

Communication between the cell surface and the nucleus is essential for regulated gene expression. In neurons, Ca(2+)-dependent gene transcription is sensitive to local Ca(2+) entry. In immune cells, excitation-transcription coupling is thought to involve global Ca(2+) signals. Here, we show that in...

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Autors principals: Ng, Siaw-Wei, Nelson, Charmaine, Parekh, Anant B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757180/
https://ncbi.nlm.nih.gov/pubmed/19584058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011692
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