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Leukotriene E(4) activates human Th2 cells for exaggerated pro-inflammatory cytokine production in response to PGD(2)
PGD(2) exerts a number of pro-inflammatory responses through a high affinity interaction with chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) and has been detected at high concentrations at sites of allergic inflammation. Since cysteinyl leukotrienes (cysLTs) are also pro...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272457/ https://ncbi.nlm.nih.gov/pubmed/22174450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102474 |
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