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Malaria impairs resistance to Salmonella through heme- and heme oxygenase-dependent dysfunctional granulocyte mobilization

In sub-Saharan Africa, invasive non-Typhoid Salmonella (NTS) is a common and often fatal complication of Plasmodium falciparum infection. Induction of heme oxygenase-1 (HO-1) mediates tolerance to the cytotoxic effects of heme during malarial hemolysis but might impair resistance to NTS by limiting...

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Detalhes bibliográficos
Main Authors: Cunnington, A. J., de Souza, J.B., Walther, R-M., Riley, E. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272454/
https://ncbi.nlm.nih.gov/pubmed/22179318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2601
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