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Activation of chemokine and inflammatory cytokine response in HCV-infected hepatocytes depends on TLR3 sensing of HCV dsRNA intermediates

Chemokines and inflammatory cytokines are key regulators of immunity and inflammation during viral infections. Hepatitis C virus (HCV) is a hepatotropic RNA virus frequently associated with chronic liver inflammation and hepatocellular carcinoma. Intrahepatic levels of chemokines and cytokines are e...

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Detalhes bibliográficos
Main Authors: Li, Kui, Li, Nan L., Wei, Dahai, Pfeffer, Susan R., Fan, Meiyun, Pfeffer, Lawrence M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272326/
https://ncbi.nlm.nih.gov/pubmed/22030901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24763
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