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Channel-Opening Kinetic Mechanism of Wild-Type GluK1 Kainate Receptors and a C-Terminal Mutant

GluK1 is a kainate receptor subunit in the ionotropic glutamate receptor family and can form functional channels when expressed, for instance, in HEK-293 cells. However, the channel-opening mechanism of GluK1 is poorly understood. One major challenge to studying the GluK1 channel is its apparent low...

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Autores principales: Han, Yan, Wang, Congzhou, Park, Jae Seon, Niu, Li
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272274/
https://ncbi.nlm.nih.gov/pubmed/22191429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201446z
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