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Allenyl Azide Cycloaddition Chemistry: Application to the Total Synthesis of (±)-Meloscine

[Image: see text] The pentacyclic alkaloid (±)-meloscine was prepared in 19 steps through a reaction sequence that features a putative azatrimethylenemethane intermediate, generated through cascade cyclization of an allenyl azide substrate, to deliver the core azabicyclo[3.3.0]octadiene substructure...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Feldman, Ken S., Antoline, Joshua F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272129/
https://ncbi.nlm.nih.gov/pubmed/22242696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol203463n
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