Spinal cord injury with unilateral versus bilateral primary hemorrhage — Effects of glibenclamide

In spinal cord injury (SCI), block of Sur1-regulated NC(Ca-ATP) channels by glibenclamide protects penumbral capillaries from delayed fragmentation, resulting in reduced secondary hemorrhage, smaller lesions and better neurological function. All published experiments demonstrating a beneficial effec...

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Hauptverfasser: Simard, J. Marc, Popovich, Phillip G., Tsymbalyuk, Orest, Gerzanich, Volodymyr
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272086/
https://ncbi.nlm.nih.gov/pubmed/22197047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.11.048
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