Noradrenergic α(1) Receptor Antagonist Treatment Attenuates Positive Subjective Effects of Cocaine in Humans: A Randomized Trial

BACKGROUND: Preclinical research implicates dopaminergic and noradrenergic mechanisms in mediating the reinforcing effects of drugs of abuse, including cocaine. The objective of this study was to evaluate the impact of treatment with the noradrenergic α(1) receptor antagonist doxazosin on the positi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Newton, Thomas F., De La Garza, Richard, Brown, Gregory, Kosten, Thomas R., Mahoney, James J., Haile, Colin N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272014/
https://ncbi.nlm.nih.gov/pubmed/22319592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030854
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