Synthesis of Amino-Benzothiaoxazepine-1,1-dioxides Utilizing a Microwave-Assisted, S(N)Ar Protocol

The development of a microwave-assisted, intermolecular S(N)Ar protocol for the synthesis of a 126-member benzothiaoxazepine-1,1-dioxide library is reported. Diversification of 12 benzothiaoxazepine-1,1-dioxides was achieved in rapid fashion utilizing a variety of 2° amines and amino alcohols to gen...

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Bibliografische gegevens
Hoofdauteurs: Rolfe, Alan, Ullah, Farman, Samarakoon, Thiwanka B., Kurtz, Ryan D., Porubsky, Patrick, Neuenswander, Benjamin, Lushington, Gerald H., Santini, Conrad, Organ, Michael G., Hanson, Paul R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271943/
https://ncbi.nlm.nih.gov/pubmed/21902243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co200076j
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