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Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses
The strength of T-cell receptor (TCR) stimulation and subsequent T-cell response depend on a combination of peptide-major histocompatibility complex (pMHC) density and potency. By comparing two different pMHC at doses yielding similar proliferation in vivo, we have highlighted unexpected differences...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3271915/ https://ncbi.nlm.nih.gov/pubmed/22223661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119763109 |
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