Coenzyme Q10 levels are low and may be associated with the inflammatory cascade in septic shock

INTRODUCTION: Mitochondrial dysfunction is associated with increased mortality in septic shock. Coenzyme Q10 (CoQ10) is a key cofactor in the mitochondrial respiratory chain, but whether CoQ10 is depleted in septic shock remains unknown. Moreover, statin therapy may decrease CoQ10 levels, but whethe...

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Main Authors: Donnino, Michael W, Cocchi, Michael N, Salciccioli, Justin D, Kim, Daniel, Naini, Ali B, Buettner, Catherine, Akuthota, Praveen
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271709/
https://ncbi.nlm.nih.gov/pubmed/21827677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10343
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