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The second extracellular loop of the dopamine D(2) receptor lines the binding-site crevice

The binding site of the dopamine D(2) receptor (D2R), like those of homologous rhodopsin-like G protein-coupled receptors (GPCRs) that bind small molecules, is contained within a water-accessible crevice formed among its seven transmembrane segments (TMs). The high-resolution structure of bovine rho...

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Autori principali: Shi, Lei, Javitch, Jonathan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC327166/
https://ncbi.nlm.nih.gov/pubmed/14704269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2237265100
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