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The second extracellular loop of the dopamine D(2) receptor lines the binding-site crevice

The binding site of the dopamine D(2) receptor (D2R), like those of homologous rhodopsin-like G protein-coupled receptors (GPCRs) that bind small molecules, is contained within a water-accessible crevice formed among its seven transmembrane segments (TMs). The high-resolution structure of bovine rho...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Shi, Lei, Javitch, Jonathan A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327166/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14704269/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2237265100
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