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Cleavage of serum response factor mediated by enteroviral protease 2A contributes to impaired cardiac function

Enteroviral infection can lead to dilated cardiomyopathy (DCM), which is a major cause of cardiovascular mortality worldwide. However, the pathogenetic mechanisms have not been fully elucidated. Serum response factor (SRF) is a cardiac-enriched transcription regulator controlling the expression of a...

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Detalhes bibliográficos
Main Authors: Wong, Jerry, Zhang, Jingchun, Yanagawa, Bobby, Luo, Zongshu, Yang, Xiangsheng, Chang, Jiang, McManus, Bruce, Luo, Honglin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271589/
https://ncbi.nlm.nih.gov/pubmed/21769134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.114
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