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Molecular basis for the inhibition of G protein-coupled inward rectifier K(+) channels by protein kinase C

G protein-coupled inward rectifier K(+) (GIRK) channels regulate cellular excitability and neurotransmission. The GIRK channels are activated by a number of inhibitory neurotransmitters through the G protein βγ subunit (G(βγ)) after activation of G protein-coupled receptors and inhibited by several...

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Publikašuvnnas:Proc Natl Acad Sci U S A
Váldodahkkit: Mao, Jinzhe, Wang, Xueren, Chen, Fuxue, Wang, Runping, Rojas, Asheebo, Shi, Yun, Piao, Hailan, Jiang, Chun
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: National Academy of Sciences 2004
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327155/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14732702/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0304827101
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