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Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses

Acquired immunity depends on proliferation and differentiation of antigen (Ag)-specific B cells in germinal centers (GCs) of lymphoid follicles in response to T cell-dependent Ags. Here, we studied the function of GC-associated nuclear protein that is selectively up-regulated in GC-B cells. B cell-s...

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Detalhes bibliográficos
Main Authors: Kuwahara, Kazuhiko, Fujimura, Satoru, Takahashi, Yoshimasa, Nakagata, Naomi, Takemori, Toshitada, Aizawa, Shinichi, Sakaguchi, Nobuo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC327142/
https://ncbi.nlm.nih.gov/pubmed/14715907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307609100
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