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T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node

Dendritic cells (DCs) ingest antigens in peripheral tissues and migrate to lymph nodes where they present MHC class II-bound antigen to CD4(+) T cells. We used two-photon microscopy to image the single-cell dynamics of interactions between DCs and T cells within intact lymph nodes in the absence of...

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Autori principali: Miller, Mark J., Hejazi, Arsalan S., Wei, Sindy H., Cahalan, Michael D., Parker, Ian
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC327133/
https://ncbi.nlm.nih.gov/pubmed/14722354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306407101
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