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T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node
Dendritic cells (DCs) ingest antigens in peripheral tissues and migrate to lymph nodes where they present MHC class II-bound antigen to CD4(+) T cells. We used two-photon microscopy to image the single-cell dynamics of interactions between DCs and T cells within intact lymph nodes in the absence of...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC327133/ https://ncbi.nlm.nih.gov/pubmed/14722354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306407101 |
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