Vaccine Protection Against Acquisition of Neutralization-Resistant SIV Challenges in Rhesus Monkeys

Preclinical studies of HIV-1 vaccine candidates have typically shown post-infection virologic control, but protection against acquisition of infection has previously only been reported against neutralization-sensitive virus challenges(1–3). Here we demonstrate vaccine protection against acquisition...

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Autors principals: Barouch, Dan H., Liu, Jinyan, Li, Hualin, Maxfield, Lori F., Abbink, Peter, Lynch, Diana M., Iampietro, M. Justin, SanMiguel, Adam, Seaman, Michael S., Ferrari, Guido, Forthal, Donald N., Ourmanov, Ilnour, Hirsch, Vanessa M., Carville, Angela, Mansfield, Keith G., Stablein, Donald, Pau, Maria G., Schuitemaker, Hanneke, Sadoff, Jerald C., Billings, Erik M., Rao, Mangala, Robb, Merlin L., Kim, Jerome H., Marovich, Mary A., Goudsmit, Jaap, Michael, Nelson L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271177/
https://ncbi.nlm.nih.gov/pubmed/22217938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10766
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