טוען...
DNA breaks and chromosome pulverization from errors in mitosis
Whether whole-chromosome aneuploidy promotes tumorigenesis has been controversial, in large part because of the paucity of insight into underlying mechanisms. Here we identify a mechanism by which mitotic chromosome segregation errors generate DNA breaks via the formation of structures called micron...
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| Main Authors: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3271137/ https://ncbi.nlm.nih.gov/pubmed/22258507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10802 |
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