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RDH10 Oxidation of Vitamin A Is a Critical Control Step in Synthesis of Retinoic Acid during Mouse Embryogenesis

Retinoic Acid (RA) is a small lipophilic signaling molecule essential for embryonic development and adult tissue maintenance. Both an excess of RA and a deficiency of RA can cause pathogenic anomalies, hence it is critical to understand the mechanisms controlling the spatial and temporal distributio...

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Détails bibliographiques
Auteurs principaux: Sandell, Lisa L., Lynn, Megan L., Inman, Kimberly E., McDowell, William, Trainor, Paul A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271098/
https://ncbi.nlm.nih.gov/pubmed/22319578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030698
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