RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development

Regulation of patterning and morphogenesis during embryonic development depends on tissue-specific signaling by retinoic acid (RA), the active form of Vitamin A (retinol). The first enzymatic step in RA synthesis, the oxidation of retinol to retinal, is thought to be carried out by the ubiquitous or...

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Detalhes bibliográficos
Main Authors: Sandell, Lisa L., Sanderson, Brian W., Moiseyev, Gennadiy, Johnson, Teri, Mushegian, Arcady, Young, Kendra, Rey, Jean-Philippe, Ma, Jian-xing, Staehling-Hampton, Karen, Trainor, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855236/
https://ncbi.nlm.nih.gov/pubmed/17473173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1533407
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