Tryptamine-Gallic Acid Hybrid Prevents Non-steroidal Anti-inflammatory Drug-induced Gastropathy: CORRECTION OF MITOCHONDRIAL DYSFUNCTION AND INHIBITION OF APOPTOSIS IN GASTRIC MUCOSAL CELLS

We have investigated the gastroprotective effect of SEGA (3a), a newly synthesized tryptamine-gallic acid hybrid molecule against non-steroidal anti-inflammatory drug (NSAID)-induced gastropathy with mechanistic details. SEGA (3a) prevents indomethacin (NSAID)-induced mitochondrial oxidative stress...

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Detalhes bibliográficos
Main Authors: Pal, Chinmay, Bindu, Samik, Dey, Sumanta, Alam, Athar, Goyal, Manish, Iqbal, Mohd. Shameel, Sarkar, Souvik, Kumar, Rahul, Halder, Kamal Krishna, Debnath, Mita Chatterjee, Adhikari, Susanta, Bandyopadhyay, Uday
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271003/
https://ncbi.nlm.nih.gov/pubmed/22157011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.307199
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