RNA Polymerase II Carboxyl-terminal Domain Phosphorylation Regulates Protein Stability of the Set2 Methyltransferase and Histone H3 Di- and Trimethylation at Lysine 36

Methylation of lysine 36 on histone H3 (H3K36) is catalyzed by the Set2 methyltransferase and is linked to transcriptional regulation. Previous studies have shown that trimethylation of H3K36 by Set2 is directed through its association with the phosphorylated repeats of the RNA polymerase C-terminal...

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Библиографические подробности
Главные авторы: Fuchs, Stephen M., Kizer, Kelby O., Braberg, Hannes, Krogan, Nevan J., Strahl, Brian D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2012
Предметы:
Gene Regulation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270979/
https://ncbi.nlm.nih.gov/pubmed/22157004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.273953
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