Up-regulation of the Neuronal Nicotinic Receptor α7 by HIV Glycoprotein 120: POTENTIAL IMPLICATIONS FOR HIV-ASSOCIATED NEUROCOGNITIVE DISORDER

Approximately 30–50% of the >30 million HIV-infected subjects develop neurological complications ranging from mild symptoms to dementia. HIV does not infect neurons, and the molecular mechanisms behind HIV-associated neurocognitive decline are not understood. There are several hypotheses to expla...

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Main Authors: Ballester, Leomar Y., Capó-Vélez, Coral M., García-Beltrán, Wilfredo F., Ramos, Félix M., Vázquez-Rosa, Edwin, Ríos, Raymond, Mercado, José R., Meléndez, Roberto I., Lasalde-Dominicci, José A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Neurobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270964/
https://ncbi.nlm.nih.gov/pubmed/22084248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.262543
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