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Wnt-RhoA signaling is involved in dental enamel development

Transgenic mice that express dominant negative RhoA (RhoA(DN)) in ameloblasts have hypoplastic enamel, with defects in molar cusps. β-catenin and Wnt5a were up-regulated in enamel organs of RhoA(DN) transgenic mice, which indicated that both canonical and non-canonical Wnt pathways were implicated i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Peng, Li, Li, Yong, Shusterman, Kate, Kuehl, Melissa, Gibson, Carolyn W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270888/
https://ncbi.nlm.nih.gov/pubmed/22243225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0722.2011.00880.x
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