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Wnt-RhoA signaling is involved in dental enamel development
Transgenic mice that express dominant negative RhoA (RhoA(DN)) in ameloblasts have hypoplastic enamel, with defects in molar cusps. β-catenin and Wnt5a were up-regulated in enamel organs of RhoA(DN) transgenic mice, which indicated that both canonical and non-canonical Wnt pathways were implicated i...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3270888/ https://ncbi.nlm.nih.gov/pubmed/22243225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0722.2011.00880.x |
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