A Phase 2a Study of Topical Perillyl Alcohol Cream for Chemoprevention of Skin Cancer

Chemopreventive and antitumor properties of perillyl alcohol (POH) studied preclinically indicate that topical POH inhibits both ultraviolet B (UVB)-induced murine skin carcinogenesis (squamous cell tumor models) and DMBA-induced murine melanoma (transgenic models involving tyrosinase-driven Ras). A...

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Главные авторы: Stratton, Steven P., Alberts, David S., Einspahr, Janine G., Sagerman, Paul M., Warneke, James A., Curiel-Lewandrowski, Clara, Myrdal, Paul B., Karlage, Kelly L., Nickoloff, Brian J., Brooks, Chris, Saboda, Kathylynn, Yozwiak, Michael L., Krutzsch, Mary F., Hu, Chengcheng, Bowden, G. Timothy, Bartels, Peter H.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270887/
https://ncbi.nlm.nih.gov/pubmed/20103724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-09-0183
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