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The 2S albumin allergens of Arachis hypogaea, Ara h 2 and Ara h 6, are the major elicitors of anaphylaxis and can effectively desensitize peanut-allergic mice

BACKGROUND: Ara h 2 and Ara h 6, co-purified together in a 13-25 kD fraction (Ara h 2/6; 20 kD fraction) on gel filtration chromatography, account for the majority of effector activity in a crude peanut extract (CPE) when assayed with RBL SX-38 cells sensitized with IgE from human peanut allergic se...

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Bibliographische Detailangaben
Hauptverfasser: Kulis, Mike, Chen, Xueni, Lew, Jeanney, Wang, Qian, Patel, Ojas P., Zhuang, Yonghua, Murray, Kerry S., Duncan, Mark W., Porterfield, Harry S., Burks, A. Wesley, Dreskin, Stephen C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270336/
https://ncbi.nlm.nih.gov/pubmed/22288514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2222.2011.03934.x
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