Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling

Viruses have evolved elaborate mechanisms to evade or inactivate the complex system of sensors and signaling molecules that make up the host innate immune response. Here we show that human coronavirus (HCoV) NL63 and severe acute respiratory syndrome (SARS) CoV papain-like proteases (PLP) antagonize...

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Bibliografski detalji
Glavni autori: Sun, Li, Xing, Yaling, Chen, Xiaojuan, Zheng, Yang, Yang, Yudong, Nichols, Daniel B., Clementz, Mark A., Banach, Bridget S., Li, Kui, Baker, Susan C., Chen, Zhongbin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270028/
https://ncbi.nlm.nih.gov/pubmed/22312431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030802
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